Intelligence for IBD, GI & Colorectal Specialists

Inflammatory bowel disease trials
recruiting in the United States

Up-to-date overview of clinical trials in Crohn's disease, ulcerative colitis, and other forms of inflammatory bowel disease (IBD) recruiting patients in the United States — automatically compiled from ClinicalTrials.gov. Refer eligible patients to participating research centers.

Active trials

1232

US sites

Indications covered

BR trials

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89 studies found

Fase 1, Fase 2Crohn DiseaseUS 2 sites in the US

Autologous Stem Cell Transplantation for Crohn's Disease

Paul Szabolcs

📍 Pittsburgh👥 20 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1, Fase 2Doenca de CrohnUS 1 site in the US

An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

National Institute of Allergy and Infectious Diseases (NIAID)

📍 Bethesda👥 35 participants📅 Completion: 2035-06

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseUS 1 site in the US

Autologous Stem Cell Transplant for Crohn's Disease

Aaron Etra

📍 New York👥 50 participants📅 Completion: 2028-10

View details →Refer patient →ClinicalTrials.gov ↗

N/DColite UlcerativaUS 1 site in the US

The Influence of a Fasting Mimicking Diet on Ulcerative Colitis

Stanford University

📍 Palo Alto👥 75 participants📅 Completion: 2027-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1, Fase 2Crohn DiseaseUS 1 site in the US

Stem Cell Transplantation in Crohn's Disease

Cedars-Sinai Medical Center

📍 Los Angeles👥 15 participants📅 Completion: 2027-09

View details →Refer patient →ClinicalTrials.gov ↗

N/DDoenca de CrohnColite UlcerativaUS 1 site in the US

Inflammatory Bowel Disease (IBD) Research Registry

University of Pittsburgh

📍 Pittsburgh👥 5000 participants📅 Completion: 2030-05

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1, Fase 2Crohn DiseaseUS 3 sites in the US

Low Dose IL-2 for the Treatment of Crohn's Disease

Boston Children's Hospital

📍 Boston, New York👥 30 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 4Ulcerative ColitisUS 4 sites in the US

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis

Bausch Health Americas, Inc.

📍 Garden Grove, Greenville, Indianapolis, The Bronx👥 70 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUlcerative ColitisColite IndeterminadaUS 1 site in the US

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

Boston Children's Hospital

📍 Boston👥 50 participants📅 Completion: 2024-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Ulcerative ColitisUS 1 site in the US

Evaluation the Safety and Efficacy of Lyophilized Fecal Microbiota Transplantation Administered Orally for Prevention of Relapse or Intestinal Inflammation in Adults With Ulcerative Colitis

The University of Texas Health Science Center, Houston

📍 Houston👥 58 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DColite UlcerativaDoenca de CrohnArtrite ReumatoideUS 1 site in the US

Regulation of Mucosal Healing in Inflammatory Bowel Disease

Terrence A Barrett

📍 Lexington👥 60 participants📅 Completion: 2026-06

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUlcerative ColitisInflammatory Bowel Disease UnclassifiedUS 1 site in the US

Registry and Biorepository for IBD in Central Texas

University of Texas at Austin

📍 Austin👥 1000 participants📅 Completion: 2030-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Colite UlcerativaObesidadeUS 1 site in the US

Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients

University of California, San Diego

📍 La Jolla👥 40 participants📅 Completion: 2024-06

View details →Refer patient →ClinicalTrials.gov ↗

N/DMelanomaDoenca Inflamatoria IntestinalArtrite ReumatoideUS 1 site in the US

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

M.D. Anderson Cancer Center

📍 Houston👥 125 participants📅 Completion: 2027-02

View details →Refer patient →ClinicalTrials.gov ↗

N/DPlaque PsoriasisArtrite PsoriasicaDoenca de CrohnUS 1 site in the US

Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications

AbbVie

📍 Morrisville👥 818 participants📅 Completion: 2032-06

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Ulcerative ColitisUS 1 site in the US

The Use of Butyrate Therapy in Pediatric Ulcerative Colitis

Children's Hospital Los Angeles

📍 Los Angeles👥 10 participants📅 Completion: 2027-06

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Colite UlcerativaUS 12 sites in the US

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

Pfizer

📍 Abilene, Boston, Chicago, Cleveland, Garden Grove, Orlando, Royal Oak, San Francisco👥 36 participants📅 Completion: 2029-06

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Colite UlcerativaDoenca de CrohnUS 3 sites in the US

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Takeda

📍 Park Ridge, Phoenix, Roanoke👥 240 participants📅 Completion: 2033-02

View details →Refer patient →ClinicalTrials.gov ↗

N/DColite UlcerativaUS 1 site in the US

Nicotinamide Riboside in Ulcerative Colitis

University of Pittsburgh

📍 Pittsburgh👥 40 participants📅 Completion: 2026-06

View details →Refer patient →ClinicalTrials.gov ↗

N/DDoenca de CrohnColite UlcerativaUS 2 sites in the US

A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

Rush University Medical Center

📍 Charleston, Chicago👥 30 participants📅 Completion: 2026-09

View details →Refer patient →ClinicalTrials.gov ↗

N/DAge Related Macular DegenerationAllergiesAlpha Gal SyndromeUS 1 site in the US

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

📍 Waltham👥 20000 participants📅 Completion: 2025-10

View details →Refer patient →ClinicalTrials.gov ↗

Fase 4Crohn DiseaseUS 21 sites in the US

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Connecticut Children's Medical Center

📍 Ann Arbor, Atlanta, Baltimore, Boston, Charlotte, Cincinnati, Cleveland, Columbus👥 900 participants📅 Completion: 2028-07

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1Colite Ulcerativa AtivaUS 1 site in the US

Study to Evaluate the Fecal Microbiota Transplantation (FMT) in the Treatment of Ulcerative Colitis

The University of Texas Health Science Center, Houston

📍 Houston👥 20 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUS 1 site in the US

A Pilot Study Examining Low Sulfur Diet as Treatment for Persistent Symptoms in Quiescent Crohn's Disease

University of Michigan

📍 Ann Arbor👥 20 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 4Colite Ulcerativa Aguda GraveUS 1 site in the US

Feasibility Pilot Sequential Multiple Assignment Randomized Trial (SMART) for Acute Severe Ulcerative Colitis

Berinstein, Jeffrey

📍 Ann Arbor👥 162 participants📅 Completion: 2026-05

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Ulcerative ColitisUS 37 sites in the US

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

Gilead Sciences

📍 Boerne, Canton, Chesapeake, Chula Vista, Columbus, Coral Gables, Coronado, Dayton👥 176 participants📅 Completion: 2027-01

View details →Refer patient →ClinicalTrials.gov ↗

N/DColite UlcerativaDoenca de CrohnDoenca Inflamatoria IntestinalUS 1 site in the US

Therapeutic Endpoint in Pediatric IBD Conditions

Children's National Research Institute

📍 Washington D.C.👥 60 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 4Colite UlcerativaUS 39 sites in the US

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Takeda

📍 Asheville, Chapel Hill, Chevy Chase, Chicago, Cincinnati, Columbus, Dallas, Dothan👥 65 participants📅 Completion: 2027-07

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUS 1 site in the US

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

Seattle Children's Hospital

📍 Seattle👥 60 participants📅 Completion: 2027-04

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseUS 10 sites in the US

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

📍 Cedar Park, Fayetteville, Houston, Johnson City, Kissimmee, Lancaster, Lynchburg, Ogden👥 385 participants📅 Completion: 2028-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseUS 3 sites in the US

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

Takeda

📍 Colorado Springs, San Antonio, Tyler👥 396 participants📅 Completion: 2027-06

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseUS 23 sites in the US

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Takeda

📍 Atlanta, Bellaire, Clearwater, Decatur, Glen Burnie, Greenville, Iowa City, Lakeland👥 268 participants📅 Completion: 2026-09

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUS 11 sites in the US

VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study

Alimentiv Inc.

📍 Bellevue, Chapel Hill, Chestnut Hill, Cleveland, Evanston, Fort Worth, Iowa City, Mansfield👥 300 participants📅 Completion: 2026-06

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseUS 1 site in the US

Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

Weill Medical College of Cornell University

📍 New York👥 120 participants📅 Completion: 2028-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DUlcerative ColitisUS 1 site in the US

Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis

University of California, San Diego

📍 San Diego👥 10 participants📅 Completion: 2026-09

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseColite UlcerativaColite IndeterminadaUS 1 site in the US

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

Seattle Children's Hospital

📍 Seattle👥 200 participants📅 Completion: 2028-01

View details →Refer patient →ClinicalTrials.gov ↗

N/DColite UlcerativaUS 24 sites in the US

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Pfizer

📍 Chapel Hill, Charleston, Charlotte, Chevy Chase, Chicago, Cincinnati, Glen Burnie, Houston👥 300 participants📅 Completion: 2027-10

View details →Refer patient →ClinicalTrials.gov ↗

N/DUlcerative ColitisCrohn DiseaseUS 1 site in the US

Impact of Prebiotics in Ulcerative Colitis

University of California, Los Angeles

📍 Los Angeles👥 70 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUS 2 sites in the US

Behavioral Therapy for Crohn's Disease

Icahn School of Medicine at Mount Sinai

📍 New York👥 170 participants📅 Completion: 2027-07

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUS 2 sites in the US

Helmsley 3.0: Abbreviated MRE

Children's Hospital Medical Center, Cincinnati

📍 New York, Rochester👥 300 participants📅 Completion: 2027-02

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1Crohn DiseaseUS 1 site in the US

Effect of Statins on Crohn's Disease

Stanford University

📍 Stanford👥 20 participants📅 Completion: 2027-10

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseUS 56 sites in the US

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

AbbVie

📍 Asheville, Boise, Cedar Park, Chevy Chase, Chicago, Cincinnati, Clermont, Colorado Springs👥 540 participants📅 Completion: 2030-01

View details →Refer patient →ClinicalTrials.gov ↗

Fase 4Ulcerative ColitisCrohn DiseaseUS 76 sites in the US

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

Takeda

📍 Atlanta, Baton Rouge, Bellevue, Birmingham, Bridgeton, Brooksville, Carmel, Cedarhurst👥 400 participants📅 Completion: 2027-10

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Colite UlcerativaUS 35 sites in the US

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Eli Lilly and Company

📍 Baytown, Brooklyn, Chapel Hill, Chula Vista, Cincinnati, Colorado Springs, Coronado, Edinburg👥 140 participants📅 Completion: 2027-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1, Fase 2Ulcerative ColitisUS 24 sites in the US

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

Xencor, Inc.

📍 Albany, Beavercreek, Bradenton, Brandon, Cedar Park, Denton, Georgetown, Houston👥 270 participants📅 Completion: 2028-04

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseUS 1 site in the US

Standardized Microbiota Transplant Therapy in Crohn's Disease

University of Minnesota

📍 Minneapolis👥 120 participants📅 Completion: 2029-06

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUS 1 site in the US

A Pilot Study to Assess the Safety, Tolerability, and Efficacy of Virtual Reality for the Treatment of Abdominal Pain in Quiescent Crohn's Disease

Mayo Clinic

📍 Jacksonville👥 15 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseColite UlcerativaUS 12 sites in the US

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

Merck Sharp & Dohme LLC

📍 Bristol, Charlottesville, Garland, Liberty, Lubbock, New York, San Antonio, Southlake👥 1380 participants📅 Completion: 2037-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DDoenca Inflamatoria IntestinalColite UlcerativaDoenca de CrohnUS 1 site in the US

Family Members At INcreased-risk for Developing Inflammatory Bowel Disease

Massachusetts General Hospital

📍 Boston👥 50 participants📅 Completion: 2034-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohns DiseaseColite UlcerativaArtrite PsoriasicaUS 5 sites in the US

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Janssen Research & Development, LLC

📍 Atlanta, Cincinnati, Indianapolis, Salt Lake City👥 196 participants📅 Completion: 2031-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DUlcerative ColitisUS 8 sites in the US

Mirikizumab Real World Protocol

University of North Carolina, Chapel Hill

📍 Chapel Hill, Charleston, Denver, Iowa City, Louisville, Orlando, Rochester, San Antonio👥 100 participants📅 Completion: 2030-01

View details →Refer patient →ClinicalTrials.gov ↗

N/DColorectal CancerSiboCrohn DiseaseUS 4 sites in the US

Urine Metabolites in the Diagnosis of Disease

Luventix, Inc.

📍 Encinitas, Santa Monica, Walnut Creek👥 1250 participants📅 Completion: 2025-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1, Fase 2Crohn DiseaseUS 13 sites in the US

Treatment of Moderate to Severe Refractory Crohn's Disease

Tr1X, Inc.

📍 Ann Arbor, Chicago, Cleveland, Gainesville, Iowa City, Louisville, New York, Rochester👥 39 participants📅 Completion: 2026-01

View details →Refer patient →ClinicalTrials.gov ↗

N/DDoenca de CrohnRetocolite UlcerativaUS 2 sites in the US

Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

Mercy Medical Center

📍 Chapel Hill, New York👥 200 participants📅 Completion: 2026-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseColite UlcerativaUS 2 sites in the US

A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

Takeda

📍 Glen Burnie, Tyler👥 192 participants📅 Completion: 2029-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 4Crohn DiseaseUS 1 site in the US

Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients

University of Miami

📍 Miami👥 24 participants📅 Completion: 2027-03

View details →Refer patient →ClinicalTrials.gov ↗

N/DUlcerative ColitisUS 1 site in the US

Tailored Anti-Inflammatory (A-I) Diet for Americans With Ulcerative Colitis (UC)

University of Miami

📍 Miami👥 122 participants📅 Completion: 2030-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Doenca de CrohnUS 92 sites in the US

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Hoffmann-La Roche

📍 Arlington, Atlanta, Beavercreek, Boston, Brooksville, Brunswick, Charleston, Charlotte👥 600 participants📅 Completion: 2028-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseCrohns DiseaseUS 52 sites in the US

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Hoffmann-La Roche

📍 Baltimore, Baton Rouge, Beavercreek, Brooklyn, Charlotte, Chevy Chase, Chicago, Cleveland👥 425 participants📅 Completion: 2028-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DInflammatory Bowel DiseaseUS 1 site in the US

IBD Pregnancy Registry

CorEvitas

📍 Wilmington👥 832 participants📅 Completion: 2032-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Doenca de Crohn PerianalUS 5 sites in the US

DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease

Direct Biologics, LLC

📍 Aurora, Nashville, New York, Philadelphia, St Louis👥 36 participants📅 Completion: 2027-07

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseObesidade ou SobrepesoUS 33 sites in the US

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Eli Lilly and Company

📍 Anaheim, Chevy Chase, Cordova, Dothan, Fayetteville, Greenville, Idaho Falls, Indianapolis👥 290 participants📅 Completion: 2028-05

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseUS 20 sites in the US

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

Sanofi

📍 Boston, Chapel Hill, Escondido, Fredericksburg, Harrisburg, Iowa City, Kansas City, Kissimmee👥 99 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Colite UlcerativaUS 21 sites in the US

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

Sanofi

📍 Boston, Chapel Hill, Escondido, Harrisburg, Houston, Iowa City, Jacksonville, Kissimmee👥 99 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DSaudavelDoenca de CrohnDoenca Inflamatoria IntestinalUS 1 site in the US

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

Massachusetts General Hospital

📍 Boston👥 10 participants📅 Completion: 2027-04

View details →Refer patient →ClinicalTrials.gov ↗

N/DUlcerative ColitisUS 1 site in the US

Effects of Pomegranate Juice on Ulcerative Colitis

University of California, Los Angeles

📍 Los Angeles👥 30 participants📅 Completion: 2027-10

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseUS 94 sites in the US

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Sanofi

📍 Atlanta, Baton Rouge, Canoga Park, Canton, Chapel Hill, Charlotte, Chesterfield, Clermont👥 980 participants📅 Completion: 2029-05

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Ulcerative ColitisUS 28 sites in the US

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Sanofi

📍 Baton Rouge, Chesterfield, Colorado Springs, Columbus, Coronado, Fayetteville, Fort Myers, Kissimmee👥 671 participants📅 Completion: 2028-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Ulcerative ColitisUS 36 sites in the US

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Eli Lilly and Company

📍 Anaheim, Bellevue, Boston, Cedar Park, Clinton Township, Colorado Springs, Cordova, Dayton👥 252 participants📅 Completion: 2027-05

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUlcerative ColitisIndeterminate ColitisUS 1 site in the US

Evaluation of the SMART IBD App in Pediatric IBD

Children's Hospital Medical Center, Cincinnati

📍 Cincinnati👥 70 participants📅 Completion: 2027-02

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2, Fase 3Crohn DiseaseUS 55 sites in the US

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

Janssen Research & Development, LLC

📍 Anaheim, Atlanta, Austin, Canoga Park, Carmel, Carrollton, Chandler, Chapel Hill👥 1092 participants📅 Completion: 2028-09

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUlcerative ColitisIbd UnclassifiedUS 4 sites in the US

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

University of North Carolina, Chapel Hill

📍 Chapel Hill, Charlotte, Durham, Pittsburgh👥 1100 participants📅 Completion: 2028-09

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseUlcerative ColitisIbd UnclassifiedUS 1 site in the US

Assessment and Educational Intervention to Reduce Ultra-processed Food Consumption in Pediatric Patients With IBD

Connecticut Children's Medical Center

📍 Hartford👥 120 participants📅 Completion: 2026-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 4Colite Ulcerativa Aguda GraveUS 1 site in the US

Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction for Inpatients and Outpatients With Acute Severe Ulcerative Colitis

Berinstein, Jeffrey

📍 Ann Arbor👥 110 participants📅 Completion: 2029-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 1Crohn DiseaseFibrose IntestinalUS 1 site in the US

68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease

Mayo Clinic

📍 Rochester👥 45 participants📅 Completion: 2027-02

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseDismenorreia PrimariaUS 1 site in the US

Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)

University of North Carolina, Chapel Hill

📍 Chapel Hill👥 24 participants📅 Completion: 2028-07

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Ulcerative ColitisUS 1 site in the US

Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies

Northwestern University

📍 Chicago👥 180 participants📅 Completion: 2028-12

View details →Refer patient →ClinicalTrials.gov ↗

N/DCrohn DiseaseColite UlcerativaArtrite ReumatoideUS 1 site in the US

Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis

Fuller Research Foundation

📍 Charlottesville👥 160 participants📅 Completion: 2027-09

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Colite UlcerativaDoenca de CrohnUS 9 sites in the US

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

Eli Lilly and Company

📍 Atlanta, Boston, Fort Worth, Hartford, New York, San Francisco, St Louis, Waltham👥 150 participants📅 Completion: 2030-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseUS 11 sites in the US

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Eli Lilly and Company

📍 Atlanta, Burlington, Dayton, Fort Worth, Hartford, Indianapolis, New York, Philadelphia👥 90 participants📅 Completion: 2027-12

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseUS 12 sites in the US

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

Janssen Research & Development, LLC

📍 Atlanta, Boston, Colchester, Fort Worth, Hartford, Indianapolis, Los Angeles, Morristown👥 120 participants📅 Completion: 2027-10

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseUS 12 sites in the US

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

AbbVie

📍 Aurora, Boston, Chapel Hill, Cleveland, Hartford, Indianapolis, Minneapolis, New York👥 110 participants📅 Completion: 2027-06

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Crohn DiseaseUS 71 sites in the US

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Merck Sharp & Dohme LLC

📍 Anaheim, Ann Arbor, Atlanta, Aurora, Bethesda, Boston, Chapel Hill, Charlotte👥 1200 participants📅 Completion: 2028-10

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Colite UlcerativaUS 69 sites in the US

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

Hoffmann-La Roche

📍 Apple Valley, Atlanta, Beavercreek, Brooklyn, Charlotte, Chesapeake, Cincinnati, Cleveland👥 350 participants📅 Completion: 2027-01

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Crohn DiseaseUS 19 sites in the US

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.

Sanofi

📍 Ann Arbor, Bristol, Charleston, Clermont, Flowood, Glenview, Greenville, Gurnee👥 260 participants📅 Completion: 2027-07

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Colite UlcerativaUS 19 sites in the US

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

Sanofi

📍 Ann Arbor, Bristol, Charleston, Clermont, Glenview, Gurnee, Katy, Kissimmee👥 204 participants📅 Completion: 2027-07

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Ulcerative ColitisObesidade ou SobrepesoUS 36 sites in the US

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Eli Lilly and Company

📍 Anaheim, Chevy Chase, Chicago, Cordova, Dothan, Fayetteville, Greenville, Idaho Falls👥 350 participants📅 Completion: 2028-04

View details →Refer patient →ClinicalTrials.gov ↗

Fase 2Colite UlcerativaUS 8 sites in the US

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Genentech, Inc.

📍 Chicago, Colorado Springs, Fresh Meadows, Kissimmee, Lancaster, Monroe, Salt Lake City, San Diego👥 224 participants📅 Completion: 2027-08

View details →Refer patient →ClinicalTrials.gov ↗

Fase 3Colite UlcerativaUS 51 sites in the US

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Janssen Research & Development, LLC

📍 Anaheim, Atlanta, Austin, Carmel, Carrollton, Chandler, Chapel Hill, Charlotte👥 882 participants📅 Completion: 2028-01

View details →Refer patient →ClinicalTrials.gov ↗

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Inflammatory bowel disease trialsrecruiting in the United States

Autologous Stem Cell Transplantation for Crohn's Disease

An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

Autologous Stem Cell Transplant for Crohn's Disease

The Influence of a Fasting Mimicking Diet on Ulcerative Colitis

Stem Cell Transplantation in Crohn's Disease

Inflammatory Bowel Disease (IBD) Research Registry

Low Dose IL-2 for the Treatment of Crohn's Disease

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

Evaluation the Safety and Efficacy of Lyophilized Fecal Microbiota Transplantation Administered Orally for Prevention of Relapse or Intestinal Inflammation in Adults With Ulcerative Colitis

Regulation of Mucosal Healing in Inflammatory Bowel Disease

Registry and Biorepository for IBD in Central Texas

Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications

The Use of Butyrate Therapy in Pediatric Ulcerative Colitis

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Nicotinamide Riboside in Ulcerative Colitis

A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Study to Evaluate the Fecal Microbiota Transplantation (FMT) in the Treatment of Ulcerative Colitis

A Pilot Study Examining Low Sulfur Diet as Treatment for Persistent Symptoms in Quiescent Crohn's Disease

Feasibility Pilot Sequential Multiple Assignment Randomized Trial (SMART) for Acute Severe Ulcerative Colitis

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

Therapeutic Endpoint in Pediatric IBD Conditions

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study

Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Impact of Prebiotics in Ulcerative Colitis

Behavioral Therapy for Crohn's Disease

Helmsley 3.0: Abbreviated MRE

Effect of Statins on Crohn's Disease

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

Standardized Microbiota Transplant Therapy in Crohn's Disease

A Pilot Study to Assess the Safety, Tolerability, and Efficacy of Virtual Reality for the Treatment of Abdominal Pain in Quiescent Crohn's Disease

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

Family Members At INcreased-risk for Developing Inflammatory Bowel Disease

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Mirikizumab Real World Protocol

Urine Metabolites in the Diagnosis of Disease

Treatment of Moderate to Severe Refractory Crohn's Disease

Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients

Tailored Anti-Inflammatory (A-I) Diet for Americans With Ulcerative Colitis (UC)

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

IBD Pregnancy Registry

DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

Effects of Pomegranate Juice on Ulcerative Colitis

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Evaluation of the SMART IBD App in Pediatric IBD

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

Assessment and Educational Intervention to Reduce Ultra-processed Food Consumption in Pediatric Patients With IBD

Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction for Inpatients and Outpatients With Acute Severe Ulcerative Colitis

68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease

Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)

Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies

Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

Inflammatory bowel disease trials
recruiting in the United States